Thymidylate synthase gene from Lactococcus lactis as a genetic marker: an alternative to antibiotic resistance genes.

doi:10.1128/aem.56.7.2164-2169.1990

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Article

Thymidylate synthase gene from Lactococcus lactis as a genetic marker: an alternative to antibiotic resistance genes.

Applied and environmental microbiology - 1 Jul 1990

Ross P, O'Gara F, Condon S

Abstract excerpt

The potential of the thymidylate synthase thyA gene cloned from Lactococcus lactis subsp. lactis as a possible alternative selectable marker gene to antibiotic resistance markers has been examined. The thyA mutation is a recessive lethal one; thyA mutants cannot survive in environments containing...

Topics

Cloning, Molecular
Drug Resistance, Microbial
Gene Expression
Genes, Bacterial
Genetic Markers
Genetic Vectors
Lactococcus lactis
Mutation
Plasmids
Thymidylate Synthase

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