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Article

Characterization of a 5-azacytidine-induced developmental Aspergillus fumigatus variant.

Virulence - 1 Jan 2000

Ben-Ami Ronen, Varga Varga, Lewis Russell E, May Gregory S, Nierman William C, Kontoyiannis Dimitrios P

Abstract excerpt

The hypomethylating agent 5-azacytidine (5AC) is widely used in patients at risk of invasive mycoses. We sought to determine whether 5AC affects the developmental competence and virulence of Aspergillus fumigatus. Incubation of A. fumigatus strain 293 with 5AC induced high-frequency conversion to...

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Source

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Identifiers

PMID: 21178435
DOI: 10.4161/viru.1.3.11750
PMCID: PMC3265789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21178435-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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