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Article

RAC2 and primary human immune deficiencies.

Journal of leukocyte biology - 1 Aug 2020

Lougaris Vassilios, Baronio Manuela, Gazzurelli Luisa, Benvenuto Alessio, Plebani Alessandro

Abstract excerpt

RAC2 is a GTPase that is exclusively expressed in hematopoietic cells. Animal models have suggested important roles for RAC2 in the biology of different cell types, such as neutrophils and lymphocytes. Primary immunodeficiencies represent "experimentum naturae" and offer priceless insight on the function of the human immune system. Mutations in RAC2 have been identified in a small number of patients giving rise...

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Identifiers

PMID: 32542921
DOI: 10.1002/JLB.5MR0520-194RR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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