Influence of the G2m(n) allotype and age on IgG subclass distribution in antibodies to dietary proteins in children with coeliac disease.

doi:10.1111/j.1365-2249.1990.tb03335.x

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Article

Influence of the G2m(n) allotype and age on IgG subclass distribution in antibodies to dietary proteins in children with coeliac disease.

Clinical and experimental immunology - 1 Aug 1990

Rautonen N, Rautonen J, Savilahti E

Abstract excerpt

In 47 children with coeliac disease, IgG1 was the dominant IgG subclass (mean 61%) in antibodies to gliadin, a protein component of wheat; IgG2 (22%) and IgG3 (15%) were also found. Very little IgG4 (3%) was detected. Both G2m(n)allotype and the age of the patient had an independent effect on the subclass distribution. The effects of these two factors seem similar to those described earlier on responses to...

Topics

Adolescent
Adult
Aging
Analysis of Variance
Celiac Disease
Child
Child, Preschool
Dietary Proteins
Genotype
Gliadin
Humans
Immunodiffusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin G

Immunoglobulin Gm Allotypes

Infant

Lactoglobulins

Ovalbumin

Regression Analysis

Source

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Identifiers

PMID: 2117511
DOI: 10.1111/j.1365-2249.1990.tb03335.x
PMCID: PMC1535049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2117511-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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