Article
Immunoglobulin heavy-chain allotypes play a role in the clinical history of celiac disease.
Experimental and clinical immunogenetics - 1 Jan 1991
Caruso C, Candore G, Lio D, Modica M A, Cataldo F, Maltese I, Marino V, Albeggiani A
Abstract excerpt
We studied the role of the immunoglobulin heavy-chain allotypes in the evolution of celiac disease. Particularly the Gm(fb) phenotype was investigated since this phenotype is able to determine the breadth of immune response against alpha-gliadin antigen. The results show that weight percentiles and intestinal absorption as assessed by xylose test are influenced by Gm(fb) phenotype suggesting that Gm(fb) genes...
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