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Article

Effect of classification based on combination of mutation and methylation in colorectal cancer prognosis.

Oncology reports - 1 Mar 2011

Aoyagi Haruhiko, Iida Satoru, Uetake Hiroyuki, Ishikawa Toshiaki, Takagi Yoko, Kobayashi Hirotoshi, Higuchi Tetsuro, Yasuno Masamichi, Enomoto Masayuki, Sugihara Kenichi

Abstract excerpt

Colorectal cancer (CRC) is caused by an accumulation of genetic alterations and epigenetic alterations. The molecular classification of CRCs based on genetic alterations and epigenetic alterations is evolving. Here, we examined mutations and methylation status in CRCs to determine if the combinat...

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Identifiers

PMID: 21174064
DOI: 10.3892/or.2010.1118

Genes

EGFR
AKT1
BRAF
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21174064-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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