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Flow Cytometry Rapidly Identifies All Acute Promyelocytic Leukemias With High Specificity Independent of Underlying Cytogenetic Abnormalities

20 Dec 2010

Abstract excerpt

Acute promyelocytic leukemia (APL) is a highly aggressive disease requiring prompt diagnosis and specific early intervention. Immunophenotyping by flow cytometry (FCM) facilitates a rapid diagnosis, but commonly used criteria are neither sufficiently sensitive nor specific. With an antibody panel for diagnostic screening in routine practice, we found all 149 APL cases in this study exhibited a unique...

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PMID: 21173127
DOI: 10.1309/ajcpw9tslqnczavt

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