Article
Protein glycosylation in heat-sensitive and thermotolerance-deficient mutants of Chinese hamster ovary cells.
Journal of cell science - 1 Apr 1990
Henle K J, Nagle W A, Bedford J S, Harvey W F
Abstract excerpt
Chinese hamster ovary (CHO) cells are capable of developing a high degree of thermotolerance in response to appropriate heat conditioning. In this study we examined the relationship between thermotolerance development and protein glycosylation using four sublines of CHO cells. Two of these CHO sublines are characterized by an increased heat sensitivity and impaired cellular capacity for thermotolerance...
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