Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating age-associated phenotypes in a mouse model of protein dyshomeostasis.

Methods (San Diego, Calif.) - 1 Mar 2011

Min Jin-Na, Patterson Cam

Abstract excerpt

Proteotoxicity caused by an imbalanced protein quality control surveillance system is believed to contribute to the phenotypes associated with aging as well as many neurodegenerative diseases. Understanding and monitoring the impact of proteotoxicity in these processes offers researchers keen insight into the biology of aging, as well as other conditions that share similar pathological etiologies. In Section 2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Body Composition
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Assays

Share to Homeostasis

Share to Immunoblotting

Share to Neurodegenerative Diseases

Share to Proteasome Endopeptidase Complex

Source

Open in PubMed Open full text

Identifiers

PMID: 21167942
DOI: 10.1016/j.ymeth.2010.12.012
PMCID: PMC3057337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating age-associated phenotypes in a mouse model of protein dyshomeostasis.PMID 21167942Read ↗

Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse ModelSemantic proximity Read ↗

Proteostasis Dysfunction in Aged Mammalian Cells. The Stressful Role of InflammationSemantic proximity Read ↗

Proteostasis and ageing: insights from long‐lived mutant miceSemantic proximity Read ↗

Comparative Study of Protein Aggregation Propensity and Mutation Tolerance Between Naked Mole-Rat and Mouse.Semantic proximity Read ↗

Comparative study of protein aggregation propensity and mutation tolerance between naked mole-rat and mouseSemantic proximity Read ↗

The Role of MicroRNAs in Proteostasis Decline and Protein Aggregation during Brain and Skeletal Muscle AgingSemantic proximity Read ↗

Analysis of Brain Protein Stability Changes in a Mouse Model of Alzheimer's Disease.Semantic proximity Read ↗

Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by agingSemantic proximity Read ↗

Protein homeostasis in aging and cancerSemantic proximity Read ↗

Proteostasis-associated aging: lessons from a Drosophila modelSemantic proximity Read ↗

Proteostasis and longevity: when does aging really begin?Semantic proximity Read ↗

Proteostasis and longevity: when does aging really begin?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.