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Article

Influence of CLOCK on cytotoxicity induced by diethylnitrosamine in mouse primary hepatocytes.

Toxicology - 27 Feb 2011

Matsunaga Naoya, Kohno Yumiko, Kakimoto Keisuke, Hayashi Akane, Koyanagi Satoru, Ohdo Shigehiro

Abstract excerpt

The Clock gene is a core clock factor that plays an essential role in generating circadian rhythms. In the present study, it was investigated whether the Clock gene affects the response to diethylnitrosamine (DEN)-induced cytotoxicity using mouse primary hepatocytes. DEN-induced cytotoxicity, aft...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21167249
DOI: 10.1016/j.tox.2010.12.005

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21167249-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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