Article
The energetic contribution of induced electrostatic asymmetry to DNA bending by a site-specific protein.
Journal of molecular biology - 18 Feb 2011
Hancock Stephen P, Hiller David A, Perona John J, Jen-Jacobson Linda
Abstract excerpt
DNA bending can be promoted by reducing the net negative electrostatic potential around phosphates on one face of the DNA, such that electrostatic repulsion among phosphates on the opposite face drives bending toward the less negative surface. To provide the first assessment of energetic contribution to DNA bending when electrostatic asymmetry is induced by a site-specific DNA binding protein, we manipulated the...
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