Article
The paradoxical association of common polymorphisms of the renin-angiotensin system genes with risk of myocardial infarction.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology - 1 Dec 2004
Andrikopoulos George K, Richter Dimitri J, Needham Edward W, Tzeis Stylianos E, Zairis Michalis N, Gialafos Elias J, Vogiatzi Paraskeui G, Papasteriadis Evaggelos G, Kardaras Fotios G, Foussas Stefanos G, Gialafos John E, Stefanadis Christodoulos I, Toutouzas Pavlos K, Mattu Raj K
Abstract excerpt
BACKGROUND: The insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE) and the A1166C polymorphism of the angiotensin-II AT1 receptor (AT1R) have been extensively investigated as possible risk factors for myocardial infarction (MI). DESIGN AND METHODS: Genetic association, case-control study, specifically designed to investigate the association of the above-mentioned polymorphisms with risk of...
Topics
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Greece
- Humans
- Hypercholesterolemia
- Male
