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Article

A proposal for identifying the low renal uric acid clearance phenotype.

Arthritis research & therapy - 1 Jan 2010

Indraratna Praveen L, Stocker Sophie L, Williams Kenneth M, Graham Garry G, Jones Graham, Day Richard O

Abstract excerpt

Investigation of the genetic basis of hyperuricaemia is a subject of intense interest. However, clinical studies commonly include hyperuricaemic patients without distinguishing between 'over-producers' or 'under-excretors' of urate. The statistical power of studies of genetic polymorphisms of genes encoding renal urate transporters is diluted if 'over-producers' of uric acid are included. We propose that lower...

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Identifiers

PMID: 21162713
DOI: 10.1186/ar3191
PMCID: PMC3046522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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