Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors

13 Dec 2010

Abstract excerpt

A significant enrichment of CD4(+)Foxp3(+) T cells (regulatory T cells, Treg) is frequently observed in murine and human carcinomas. As Tregs can limit effective antitumor immune responses, thereby promoting tumor progression, it is important that the mechanisms underpinning intratumoral accumulation of Tregs are identified. Because of evidence gathered mostly in vitro, the conversion of conventional T cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21156649
DOI: 10.1158/0008-5472.can-10-1797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced TumorsPMID 21156649Read ↗

Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.Semantic proximity Read ↗

The T-cell Receptor Repertoire of Tumor-Infiltrating Regulatory T Lymphocytes Is Skewed Toward Public SequencesSemantic proximity Read ↗

Regulatory T cells in cancer: where are we now?Semantic proximity Read ↗

Reprogramming of regulatory T cells in inflammatory tumor microenvironment: can it become immunotherapy turning point?Semantic proximity Read ↗

Induced regulatory T cells in inhibitory microenvironments created by cancerSemantic proximity Read ↗

Convergences and Divergences of Thymus- and Peripherally Derived Regulatory T Cells in CancerSemantic proximity Read ↗

Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.Semantic proximity Read ↗

A linear ontogeny accounts for the development of naive, memory and tumour-infiltrating regulatory T cells in miceSemantic proximity Read ↗

Oncogenic BRAFV600E Governs Regulatory T-cell Recruitment during Melanoma Tumorigenesis.Semantic proximity Read ↗

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation.Semantic proximity Read ↗

Tumors accumulate expanded GATA3-dependent tissue TregsSemantic proximity Read ↗

CD25+ CD4+ regulatory T-cells in cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.