Article
B lymphoblastic leukemia with ETV6 amplification.
Cancer genetics and cytogenetics - 1 Dec 2010
Chae Hyojin, Kim Myungshin, Lim Jihyang, Kim Yonggoo, Han Kyungja, Lee Seok
Abstract excerpt
We present a case of acute lymphoblastic leukemia caused by ETV6 amplification. Although the cytogenetic result revealed complex karyotype, multicolor fluorescence in situ hybridization and high-resolution multicolor banding supported amplification of a gene on 12p13. Fluorescence in situ hybridization with ETV6 probe confirmed the amplification. ETV6 generally plays as tumor-suppressor gene in leukemia. Their...
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