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Article

Association of BLK (rs13277113, rs2248932) polymorphism with systemic lupus erythematosus: a meta-analysis.

Molecular biology reports - 1 Oct 2011

Fan Ye, Tao Jin-Hui, Zhang Li-Ping, Li Lian-Hong, Ye Dong-Qing

Abstract excerpt

The B-cell lymphocyte kinase (BLK) is a src-family protein tyrosine kinase specifically expressed in B-lineage cells that has been implicated in the pathogenesis of systemic lupus erythematosus (SLE) and has been investigated in numerous ethnically diverse studies. However, genetic association st...

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Source

Identifiers

PMID: 21152986
DOI: 10.1007/s11033-010-0573-5

Genes

BLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21152986-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Association of BLK (rs13277113, rs2248932) polymorphism with systemic lupus erythematosus: a meta-analysis.PMID 21152986Read ↗

Association between BLK polymorphisms and susceptibility to SLE : A meta-analysis.Semantic proximity Read ↗

B-cell lymphocyte kinase polymorphisms rs13277113, rs2736340, and rs4840568 and risk of autoimmune diseases: A meta-analysis.Semantic proximity Read ↗

Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population.Semantic proximity Read ↗

BLK pathway-associated rs13277113 GA genotype is more frequent in SLE patients and associated with low gene expression and increased flares.Semantic proximity Read ↗

Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations.Semantic proximity Read ↗

Polymorphisms of BLK are associated with renal disorder in patients with systemic lupus erythematosus.Semantic proximity Read ↗

The association of the BLK gene with SLE was replicated in Chinese Han.Semantic proximity Read ↗

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.Semantic proximity Read ↗

Association of BLK and BANK1 gene polymorphisms with systemic lupus erythematous in Egyptian patients.Semantic proximity Read ↗

C8orf13-BLK is a genetic risk locus for systemic sclerosis and has additive effects with BANK1: results from a large french cohort and meta-analysis.Semantic proximity Read ↗

MTHFR polymorphisms (rs1801133) and systemic lupus erythematosus risk: A meta-analysis.Semantic proximity Read ↗

Interaction analysis between BLK rs13277113 polymorphism and BANK1 rs3733197 polymorphism, MMEL1/TNFRSF14 rs3890745 polymorphism in determining susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

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