Article
BLK pathway-associated rs13277113 GA genotype is more frequent in SLE patients and associated with low gene expression and increased flares.
Clinical rheumatology - 1 Jan 2017
Pamuk Omer Nuri, Gurkan Hakan, Pamuk Gulsum Emel, Tozkır Hilmi, Duymaz Julide, Yazar Metin
Abstract excerpt
We aimed to evaluate the relationship between some important genetic variations and expressions of these genes in our SLE population. We also determined their association with clinical parameters. Eighty-four SLE patients (79 F, 5 M) and 105 healthy controls (98 F, 7 M) were included in the study. rs13277113, rs2736340, rs7829816, rs6983130, rs2613310, and polymorphisms, gene expressions of Src family...