Article
Peripheral and central augmentation indexes in relation to the CYP4F2 polymorphisms in Chinese.
Journal of hypertension - 1 Mar 2011
Hu Bang-Chuan, Li Yan, Li Fa-Hong, Zhang Yi, Sheng Chang-Sheng, Fan Hong-Qi, Wang Ji-Guang
Abstract excerpt
OBJECTIVE: Cytochrome (CYP) 4F2 isoform is a key metabolizing enzyme for the renal 20-hydroxyeicosatetraenoic acid (20-HETE), which, as an endogenous vasoconstrictor, may influence properties of the peripheral muscular arteries and arterioles. We, therefore, investigated the CYP4F2 polymorphisms in relation to arterial wave reflections, as measured by augmentation indexes (AIx) in Chinese. METHODS: We performed...
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