CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population.

doi:10.1016/j.pnpbp.2010.03.009

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Article

CYP4F2 gene V433M polymorphism is associated with ischemic stroke in the male Northern Chinese Han population.

Progress in neuro-psychopharmacology & biological psychiatry - 30 May 2010

Deng Shumin, Zhu Gang, Liu Fang, Zhang Hui, Qin Xue, Li Lei, Zhiyi He

Abstract excerpt

BACKGROUND: CYP4F2 is a member of the cytochrome P450 enzymes and is responsible for metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE); 20-HETE plays a role in the regulation of vascular tone in the cerebral, coronary, and renal circulation. The present study aimed to evaluate whether or not the CYP4F2 gene polymorphism V433M (rs2108622) is involved in ischemic stroke in the Northern...

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PMID: 20227456
DOI: 10.1016/j.pnpbp.2010.03.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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