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Immunogenicity of embryonic stem cell-derived progenitors after transplantation

10 Dec 2010

Abstract excerpt

PURPOSE OF REVIEW: This review focuses on the immunogenicity of embryonic stem cell (ESC)-derived progenitors and the impact of the immune response on applications of cell replacement therapy (CRT). Possible strategies to induce immunological tolerance to ESC-derived progenitor cells will also be discussed. RECENT FINDINGS: Evidence for the differential epigenetic control of major histocompatibility (MHC) and...

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PMID: 21150615
DOI: 10.1097/mot.0b013e3283424faa

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