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The Potential for Immunogenicity of Autologous Induced Pluripotent Stem Cell-derived Therapies

21 Dec 2013

Abstract excerpt

Induced pluripotent stem cell (iPSC) technology offers the promise of immune-matched cell therapies for a wide range of diseases and injuries. It is generally assumed that cells derived from autologous iPSCs will be immune-privileged. However, there are reasons to question this assumption, including recent studies that have tested iPSC immunogenicity in various ways with conflicting results. Understanding the...

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PMID: 24362036
DOI: 10.1074/jbc.r113.509588

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