Article
Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.
Veterinary pathology - 1 Jul 2011
Lahousse S A, Hoenerhoff M, Collins J, Ton T-V T, Masinde T, Olson D, Rebolloso Y, Koujitani T, Tomer K B, Hong H-H L, Bucher J, Sills R C
Abstract excerpt
Liver tumors from a previous National Toxicology Program study were examined using global gene expression and mutation analysis to define the mechanisms of carcinogenesis in mice exposed to oxazepam. Five hepatocellular adenomas and 5 hepatocellular carcinomas from male B6C3F1 mice exposed to 500...
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