Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice.

doi:10.1016/s0041-008x(03)00170-4

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Article

Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice.

Toxicology and applied pharmacology - 15 Jul 2003

Anna Colleen H, Iida Mari, Sills Robert C, Devereux Theodora R

Abstract excerpt

In this study we used liver neoplasms induced by several chemical carcinogens to investigate potential nuclear targets associated with beta-catenin/Wnt signaling and potential membrane-associated beta-catenin binding partners. Strong expression of cyclin D1, in a pattern similar to that observed previously for beta-catenin, was observed by Western analysis for all five hepatoblastomas examined regardless of...

Topics

Adenoma, Liver Cell
Animals
Biomarkers, Tumor
Cadherins
Carcinoma, Hepatocellular
Cyclin D1
Cytoskeletal Proteins
ErbB Receptors
Genes, ras
Hepatoblastoma
Immunoenzyme Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms, Experimental

Mice

Mice, Inbred Strains

Mutation

Neoplasm Proteins

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-jun

Source

Open in PubMed

Identifiers

PMID: 12878043
DOI: 10.1016/s0041-008x(03)00170-4

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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