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Article

The potential role of VPREB1 gene copy number variation in susceptibility to rheumatoid arthritis.

Molecular immunology - 1 Jun 2011

Yim Seon-Hee, Chung Yeun-Jun, Jin Eun-Heui, Shim Seung-Cheol, Kim Ji-Young, Kim Yong-Shin, Hu Hae-Jin, Shin Seung-Hun, Pae Hyun-Ock, Zouali Moncef, Chung Hun-Tag

Abstract excerpt

Although the etiology of rheumatoid arthritis (RA) remains unknown, it has been widely suggested that RA has a genetic background. In humans, a copy number loss of 22q11.2, a region harboring the VPREB1 gene, has been suggested to be associated with several immunologic disorders, but there has been no study on the copy number variation (CNV) of the VPREB1 and its potential association with RA. Here, we explored...

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Source

Identifiers

PMID: 21144590
DOI: 10.1016/j.molimm.2010.11.009

Genes

VPREB1

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