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Article

The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness.

Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2012

Kulkarni Rima, Babaoglu Kerim, Lansdon Eric B, Rimsky Laurence, Van Eygen Veerle, Picchio Gaston, Svarovskaia Evguenia, Miller Michael D, White Kirsten L

Abstract excerpt

BACKGROUND: The registrational phase III clinical trials of the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) rilpivirine (RPV) in combination with two nucleoside/nucleotide RT inhibitors (NRTIs) found a unique genotypic resistance pattern involving the NNRTI mutation E138K with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21997204
DOI: 10.1097/QAI.0b013e31823aca74

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21997204-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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