Article
Where to go with FTO?
Trends in endocrinology and metabolism: TEM - 1 Feb 2011
Larder Rachel, Cheung M K Marcella, Tung Y C Loraine, Yeo Giles S H, Coll Anthony P
Abstract excerpt
An understanding of the mechanisms underlying body-weight regulation is crucial to tackle the growing problem of obesity. Recent technological advances in the analysis of genetic variation have given novel insights into the molecular basis of common disease. In particular, genomic variants in the fat mass and obesity-associated (FTO) gene have been consistently associated with human adiposity and metabolic...
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