Article
Single-nucleotide polymorphisms at the adiponectin locus and risk of coronary artery disease in Tunisian coronaries.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 Sept 2011
Boumaiza Imen, Omezzine Asma, Rejeb Jihène, Rebhi Lamia, Ben Rejeb Nabila, Nabli Naoufel, Ben Abdelaziz Ahmed, Boughzala Essia, Bouslama Ali
Abstract excerpt
OBJECTIVE: Adiponectin is an adipocyte-derived hormone and an essential modulator of insulin sensitivity. Several studies suggest an important role of adiponectin in the process leading to atherosclerosis, thus indicating the adiponectin gene as a potential candidate for coronary artery disease. Two single-nucleotide polymorphisms (SNPs) at the adiponectin locus (+45T/G and +276G/T) have been associated with low...
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