Article
Alzheimer's Disease-Associated SNP rs708727 in SLC41A1 May Increase Risk for Parkinson's Disease: Report from Enlarged Slovak Study.
International journal of molecular sciences - 29 Jan 2022
Cibulka Michal, Brodnanova Maria, Grendar Marian, Necpal Jan, Benetin Jan, Han Vladimir, Kurca Egon, Nosal Vladimir, Skorvanek Matej, Vesely Branislav, Stanclova Andrea, Lasabova Zora, Pös Zuzana, Szemes Tomas, Stuchlik Stanislav, Grofik Milan, Kolisek Martin
Abstract excerpt
SLC41A1 (A1) SNPs rs11240569 and rs823156 are associated with altered risk for Parkinson's disease (PD), predominantly in Asian populations, and rs708727 has been linked to Alzheimer's disease (AD). In this study, we have examined a potential association of the three aforementioned SNPs and of rs9438393, rs56152218, and (all three lying in the A1 promoter region) with PD in the Slovak population. Out...