Article
Transcriptional regulation of MHC class II genes.
International journal of clinical & laboratory research - 1 Jan 1995
Sartoris S, Accolla R S
Abstract excerpt
MHC class II molecules play a fundamental role in the homeostasis of the immune response, functioning as receptors for antigenic peptides to be presented to regulatory T cells. Both quantitative and qualitative alterations in the expression of these molecules on the cell surface dramatically affe...
Topics
- Animals
- DNA-Binding Proteins
- Gene Expression
- Genes, MHC Class II
- Genetic Complementation Test
- Humans
- Mice
- Mutation
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Transcription, Genetic