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Article

Regulation of malignant phenotype and bioenergetics by a π-electron donor-inducible mitochondrial MgATPase.

International journal of molecular medicine - 1 Feb 2011

Kun Ernest, Mendeleyev Jerome, Kirsten Eva, Hakam Alaeddin, Kun Albert M, Fekete Anna, Bauer Pal I, Dunai Zsuzsanna, Mihalik Rudolf

Abstract excerpt

The recognition of poly ADP-ribose transferase-1 (PARP-1) as an ATP sensor receiving this energy source by way of a specific adenylate kinase ATP wire (AK) from mitochondrial ATP synthase (F0F1), and directly regulating cellular mRNA and DNA synthesis, was the first step towards the identification of an effect by PARP-1 that is of fundamental significance. The molecular target of AK-ATP is Arg 34 of the Zn finger...

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PMID: 21125212
DOI: 10.3892/ijmm.2010.567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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