Article
The 5' and 3' downstream AUG region elements are required for mosquito-borne flavivirus RNA replication.
Journal of virology - 1 Feb 2011
Friebe Peter, Shi Pei-Yong, Harris Eva
Abstract excerpt
Flaviviruses require complementarity between the 5' and 3' ends of the genome for RNA replication. For mosquito-borne flaviviruses, the cyclization sequences (CS) and upstream of AUG region (UAR) elements at the genomic termini are necessary for viral RNA replication, and a third motif, the downstream of AUG region (DAR), was recently designated for dengue virus. The 3' DAR sequence is also part of a hairpin...
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