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The 5′ and 3′ Untranslated Regions of the Flaviviral Genome

6 Jun 2017

Abstract excerpt

Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals. The 11 kb 5' capped RNA genome consists of a single open reading frame (ORF), and is flanked by 5' and 3' untranslated regions (UTR). The ORF is a polyprotein that is processed into three structural and seven non-structural proteins. The UTRs have been shown to...

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PMID: 28587300
DOI: 10.3390/v9060137

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