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The Genomic 3′ UTR of Flaviviruses Is a Translation Initiation Enhancer

3 Aug 2022

Abstract excerpt

is a large group of positive, single-stranded RNA viruses that includes several important human pathogens, such as West Nile, Dengue and Zika virus. The genome of flaviviruses bears a type 1 cap structure at its 5' end, needed for the main translation initiation mechanism. Several members of the genus also use a cap-independent translation mechanism. The present work provides evidence that the WNV 5' end also...

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PMID: 35955738
DOI: 10.3390/ijms23158604

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