Article
Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization.
BMC genomics - 1 Dec 2010
Lewis Richard A, Laing Emma, Allenby Nicholas, Bucca Giselda, Brenner Volker, Harrison Marcus, Kierzek Andrzej M, Smith Colin P
Abstract excerpt
BACKGROUND: Whilst being closely related to the model actinomycete Streptomyces coelicolor A3(2), S. lividans 66 differs from it in several significant and phenotypically observable ways, including antibiotic production. Previous comparative gene hybridization studies investigating such differences have used low-density (one probe per gene) PCR-based spotted arrays. Here we use new experimentally optimised...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.