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Article

A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm.

European journal of human genetics : EJHG - 1 Mar 2011

Golledge Jonathan, Biros Erik, Warrington Nicole, Jones Gregory T, Cooper Matthew, van Rij Andre M, Palmer Lyle J, Norman Paul E

Abstract excerpt

Male gender and family history are risk factors for abdominal aortic aneurysm (AAA). We hypothesized that genes involved in sex hormones might be important in AAA. We investigated the association of aortic diameter with single-nucleotide polymorphisms (SNPs) in genes determining circulating sex hormones and their action. We genotyped 74 tagging SNPs across four genes (steroid 5α reductase, subfamily A,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21119710
DOI: 10.1038/ejhg.2010.182
PMCID: PMC3062004

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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