Article
Colorectal cancer susceptibility loci in a population-based study: Associations with morphological parameters.
The American journal of pathology - 1 Dec 2010
Ghazi Sam, von Holst Susanna, Picelli Simone, Lindforss Ulrik, Tenesa Albert, Farrington Susan M, Campbell Harry, Dunlop Malcolm G, Papadogiannakis Nikos, Lindblom Annika
Abstract excerpt
Recent genome-wide association studies have identified multiple genetic loci and single nucleotide polymorphisms (SNPs) associated with either increased or decreased risk of colorectal cancer (CRC). In the present study, our objective was to determine whether 11 of the new susceptibility CRC loci are associated with tumor morphology and to confirm these loci as distinct and etiologically different risk factors in...
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