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Article

Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis.

Journal of periodontal research - 1 Apr 2011

Sahingur S E, Xia X-J, Gunsolley J, Schenkein H A, Genco R J, De Nardin E

Abstract excerpt

BACKGROUND AND OBJECTIVE: Periodontitis is a multifactorial disease influenced partly by genetics. Activation of pattern recognition receptors (PRRs) can lead to the up-regulation of inflammatory pathways, resulting in periodontal tissue destruction. Hence, functional polymorphisms located in PRRs can explain differences in host susceptibility to periodontitis. This study investigated single nucleotide...

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Source

Identifiers

PMID: 21118416
DOI: 10.1111/j.1600-0765.2010.01327.x

Genes

TLR9
TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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