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Article

Association of Toll-like receptor 9 haplotypes with chronic periodontitis in Czech population.

Journal of clinical periodontology - 1 Feb 2010

Holla Lydie Izakovicova, Vokurka Jan, Hrdlickova Barbara, Augustin Peter, Fassmann Antonin

Abstract excerpt

AIM: Toll-like receptors (TLRs) belong to the pattern recognition receptors family of signal molecules that recognize conserved microbial structures. The aim of this study was to analyse polymorphisms in the TLR genes and their association with chronic periodontitis (CP). MATERIAL AND METHODS: Two polymorphisms (2408G/A, i.e. Arg753Gln and -16934A/T) in TLR-2 and three variants (-1486C/T, -1237C/T and+2848A/G) in...

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Source

Identifiers

PMID: 20041977
DOI: 10.1111/j.1600-051X.2009.01523.x

Genes

TLR9
TLR2

Provenance

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