Article
Spt10 and Swi4 control the timing of histone H2A/H2B gene activation in budding yeast.
Molecular and cellular biology - 1 Feb 2011
Eriksson Peter R, Ganguli Dwaipayan, Clark David J
Abstract excerpt
The expression of the histone genes is regulated during the cell cycle to provide histones for nucleosome assembly during DNA replication. In budding yeast, histones H2A and H2B are expressed from divergent promoters at the HTA1-HTB1 and HTA2-HTB2 loci. Here, we show that the major activator of HTA1-HTB1 is Spt10, a sequence-specific DNA binding protein with a putative histone acetyltransferase (HAT) domain....
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