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Article

Transcription Factor-7-Like 2 Gene Variants Affect the Metabolic Phenotypes of Polycystic Ovary Syndrome.

Annals of nutrition & metabolism - 1 Jan 2015

Gammoh Emily, Mahmood Naeema A, Madan Samira, Ebrahim Bashayer H, Mustafa Fekria E, Almawi Wassim Y

Abstract excerpt

BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrinopathy, which shares genetic features with type 2 diabetes mellitus (T2DM). Insofar as transcription factor 7-like 2 (TCF7L2) is consistently replicated T2DM susceptibility locus, this study evaluates whether common TCF7L2 variants are associated with PCOS and related metabolic features. METHODS: The association between TCF7L2 rs4506565, rs7903146,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26536002
DOI: 10.1159/000439546

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Transcription Factor-7-Like 2 Gene Variants Affect the Metabolic Phenotypes of Polycystic Ovary Syndrome.PMID 26536002Read ↗

Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systemic review and meta-analysis.Semantic proximity Read ↗

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Relationships between TCF7L2 genetic polymorphisms and polycystic ovary syndrome risk: a meta-analysis.Semantic proximity Read ↗

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Genetic variants of cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1 and transcription factor 7-like 2 are not associated with polycystic ovary syndrome in Chinese women.Semantic proximity Read ↗

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