Article
Ala499Val (C>T) and Lys939Gln (A>C) polymorphisms of the XPC gene: their correlation with the risk of primary gallbladder adenocarcinoma--a case-control study in China.
Carcinogenesis - 1 Apr 2011
Jiao Xingyuan, Ren Jianlin, Chen Hongyuan, Ma Jinping, Rao Shaoqi, Huang Ke, Wu Shengli, Fu Jian, Su Xiaokang, Luo Canqiao, Shi Jinsen, Broelsch Christoph E
Abstract excerpt
Genetic variations in the gene XPC may be associated with increased risk for gallbladder cancer (GBC). In this study, we detected two non-synonymous polymorphisms in XPC (Ala499Val and Lys939Gln) in 334 cases of GBC and 329 subjects of hospital-based age- and sex frequency-matched controls in China using a polymerase chain reaction-restriction fragment length polymorphism assay. Allelic association analysis for...
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