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Article

Mitochondrial pharma-Q-genomics: targeting the OXPHOS cytochrome b.

Drug discovery today - 1 Mar 2011

Gómez-Durán Aurora, Pacheu-Grau David, López-Pérez Manuel J, Montoya Julio, Ruiz-Pesini Eduardo

Abstract excerpt

Genetic variation in human cytochrome b generates structurally different coenzyme Q binding pockets, affects the coupling efficiency of the oxidative phosphorylation system and susceptibility to different medical conditions. As modification of coupling efficiency has already been shown to have th...

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Identifiers

PMID: 21112412
DOI: 10.1016/j.drudis.2010.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21112412-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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