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Article

Immunohistochemical surrogates for genetic alterations of CCDN1, PML, ALK, and NPM1 genes in lymphomas and acute myeloid leukemia.

Best practice & research. Clinical haematology - 1 Sept 2010

Falini Brunangelo, Martelli Maria Paola, Tiacci Enrico, Ascani Stefano, Thiede Christian, Pileri Stefano A

Abstract excerpt

The World Health Organization (WHO) classification of lympho-hemopoietic neoplasms is increasingly based on genetic criteria. Detection of tumor-associated primary genetic lesions is usually performed using the polymerase chain reaction (PCR) and/or fluorescence in-situ hybridization (FISH). This review focuses on alternative techniques for detecting genetic lesions in biopsy samples. Immunohistochemical...

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Source

Identifiers

PMID: 21112040
DOI: 10.1016/j.beha.2010.09.001

Genes

ALK
NPM1
PML
CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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