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The Utility of Immunohistochemistry for Providing Genetic Information on Tumors

24 Sept 2013

Abstract excerpt

With advances in immunohistochemical technology and growing knowledge of the molecular genetics of tumors, immunohistochemistry is playing an increasingly important role in providing genetic information for tumors. Specific chromosomal translocations can be demonstrated through detection of the protein product of one of the genes involved in gene fusion (such as BCL2, cyclin D, and ALK). Some mutations can be...

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PMID: 24065374
DOI: 10.1177/1066896913502529

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