Article
High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system.
Proceedings of the National Academy of Sciences of the United States of America - 1 May 1990
Hasemann C A, Capra J D
Abstract excerpt
A murine immunoglobulin heterodimer has been expressed in a baculovirus expression system. This was achieved by using both double infection of insect cells with separate heavy- and light-chain-expressing viruses and infection with a double-recombinant virus containing both the immunoglobulin heav...
Topics
- Animals
- Cell Line
- Genetic Vectors
- Immunoglobulin Heavy Chains
- Immunoglobulin Idiotypes
- Immunoglobulin Light Chains
- Insect Viruses
- Insecta
- Mutation
- Oligonucleotide Probes
- Promoter Regions, Genetic
- Radioimmunoassay
- Transfection
- Viral Proteins