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Article

European collaborative evaluation of the enzygnost HBsAg 6.0 assay: Performance on hepatitis B virus surface antigen variants

24 Nov 2010

Abstract excerpt

Amino acid changes within the major antigenic determinant of the hepatitis B virus (HBV) surface antigen (HBsAg) may modify eventually the antigenic properties of the protein and may have impact on the sensitivity of diagnostic assays. Modifications in the design of an assay can, however, improve significantly its ability to detect HBV mutants. One hundred forty-seven clinical samples containing HBsAg variants,...

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PMID: 21108344
DOI: 10.1002/jmv.21943

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