Article
RAD51 135G>C polymorphism and risk of sporadic colorectal cancer in Iranian population.
Journal of cancer research and therapeutics - 1 Jan 2000
Yazdanpanahi Nasrin, Salehi Rasoul, Kamali Sara
Abstract excerpt
BACKGROUND AND AIM OF STUDY: Colorectal cancer (CRC) is among the most common cancers and accounts as the second leading cause of death from cancers in the world. RAD51 plays a crucial role in double-strand breaks repair of DNA. Single nucleotide polymorphisms within this gene could influence on the potential of DNA repair and in consequence on the susceptibility to various tumors such as CRC. This is the first...
Topics
- Biomarkers, Tumor
- Case-Control Studies
- Colorectal Neoplasms
- Female
- Follow-Up Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
