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Article

Lack of association between the 135G/C RAD51 gene polymorphism and the risk of colorectal cancer among Polish population.

Polski przeglad chirurgiczny - 1 Jul 2012

Mucha Bartosz, Przybyłowska-Sygut Karolina, Dziki Lukasz, Dziki Adam, Sygut Andrzej, Majsterek Ireneusz

Abstract excerpt

One of the major causes of carcinogenesis is loss of genome stability. RAD51 in process of homologous recombination (HR) played crucial role in maintenance integrity of genome through initiate of DNA double strand breaks repair. Presence of single nucleotide polymorphism (SNP) in RAD51 gene could change the capacity of DNA repair and altered the response to damaging agents. Research on potential impact of genetic...

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Identifiers

PMID: 22935458
DOI: 10.2478/v10035-012-0060-x

Genes

RAD51

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