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Article

Arterial calcification is driven by RAGE in Enpp1-/- mice.

Journal of vascular research - 1 Jan 2011

Cecil Denise L, Terkeltaub Robert A

Abstract excerpt

BACKGROUND/AIMS: Ectopic osteochondral differentiation, driven by ENPP1-catalyzed generation of the chondrogenesis and calcification inhibitor inorganic pyrophosphate (PP(i)), promotes generalized arterial calcification of infancy. The multiligand receptor for advanced glycation end-products (RAGE), which promotes atherosclerosis and diabetic cardiovascular and renal complications, also mediates chondrocyte...

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Source

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Identifiers

PMID: 21099228
DOI: 10.1159/000318805
PMCID: PMC2997448

Genes

ENPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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