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Article

Generalized Arterial Calcification of Infancy: New Insights, Controversies, and Approach to Management.

Current osteoporosis reports - 1 Jun 2020

Boyce Alison M, Gafni Rachel I, Ferreira Carlos R

Abstract excerpt

PURPOSE OF REVIEW: This review summarizes current understanding of generalized arterial calcification of infancy (GACI), emphasizing pathophysiology, clinical presentation, and approaches and controversies in management. RECENT FINDINGS: Identification of causative ENPP1 mutations revealed that GACI arises from deficiencies in inorganic pyrophosphate (leading to calcifications) and adenosine monophosphate...

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Source

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Identifiers

PMID: 32172442
DOI: 10.1007/s11914-020-00577-4
PMCID: PMC9506683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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